ABSTRACT
Objective To investigate the medication adherence and clinical efficacy of inhaled glucocorticoids (ICS) and leukotriene receptor antagonists (LTRA) in the treatment of children with bronchial asthma ,in order to provide references for treatment options.Methods From 2015 to 2016,the clinical data of 140 cases with bronchial asthma who under the age of 14 years were retrospectively analyzed.The patients were randomly divided into the ICS group and the LTRA group according to the treatment methods ,with 70cases in each group.The patients in the ICS group were given aerosol inhalation of budesonide 1 mg added to saline 3 mL,twice per day,and reduced to inhale budesonide 0.5 mg/time,2 times/day after symptom relief.The patients in the LTRA group were given montelukast sodium chewable tablets 4mg/time at bed-time,one time a day for 3 months.According to the MARS-A compliance assessment,the compliance of patients in the treatment process was graded and the therapeutic effect was analyzed . Results In the same medication adherence , the effective treatment samples ( including good control and partial control) of the ICS group were 62 cases,and 8 cases without control and the effective rate was 98.36%.In the LTRA group,the effective treatment samples were 54 cases,and 16 cases without control and the effective rate was 89.09%. There was statistically significant difference in the effective rate between the two groups (χ2＝6.152,P＜0.05).In the same therapeutic efficacy (51 cases effective treatment of the ICS group ,54 cases effective treatment of the LTRA group),there were 50 cases with compliance in the ICS group and 62 cases in the LTRA group.The difference in the compliance was statistically significant (χ2＝7.012,P＜0.05).Conclusion All of the ICS group and the LTRA group can make effective control for childhood asthma.Through statistic process data of this experiment ,we discover that under the good medication adherence condition ,all of the treatment rates and the control level of the ICS group are better than the LTRA group.In the same therapeutic efficacy ,the medication adherence of the LTRA group is superior to the ICS group.
ABSTRACT
OBJECTIVE:To summarize and analyze the clinical outcomes of coil embolization for treating cerebral aneurismal METHODS:Authors retrieved PubMed Database(http://www.ncbi.nlm.nih.gov/PubMed)and Wanfang Database(http://www wanfangdata.com.cn)by using a computer for articles concerning coil embolization for treating cerebral aneurismal published from 1990 to 2008.The key words were"aneurysm of brain,spring ring interventional therapy,embolism"in English,and"cerebral aneurysm,embolism,circlip ring,endovascular treatment"in Chinese Duplicated studies were excluded.A total of54 articles were obtained by primary screening.According to inclusion criteria,14 articles were further summarized.RESULTS:The included 14 articles exhibited that aortocranial angiography was conducted before embolism to understand intracalvarium circulation and to measure aneurysm neck and size.Following microtubular in position,superselective angiography was not performed to avoid aneurysm rupture.It was important to select suitable catheter and guide wire.Spring ring with the same diameter as aneurysm size was selected When placed it,it should be twisted around the wall of aneurysm to form a primary"frame",which was beneficial for spiral of other spring rings in the"frame".Try to make spring ring densely plugged in aneurysm to avoid aneurysm relapse.The last spring ring should not be too long so as to avoid difficulty in complete filling-in.Before disengage,the spring ring should undergo visualization to verify that it was in the aneurysm to ensure the patency of parent artery.The operation should be light and soft Following proceeding a path,the guide wire and catheter should be slightly withdrawn a part to unload the tension induced by bending,resulting in avoiding"negligence-induced leaping forwards"that may pierce the aneurysm.CONCLUSION:Spring ring endovascular embolization is an ideal method to treat cerebral aneurysm,with characteristics of microinvasion,security,reliability and definite outcomes .